infraredz
BULA!
Just received my copy of "Kava Dermopathy" all the way from France hoping to gain some more insight, and unfortunately there isn't anything of substance in it that isn't already 'known'.
That being said, there was a pretty interesting suggestion made by Ruze that kava interferes with cholesterol metabolism which causes the skin changes which are similar to lipid-lowering drugs (referenced one in particular, triparanol).
This study, which studied the effect of triparanol on rat skin found results extremely similar to kava dermopathy.
http://www.jlr.org/content/4/2/160.full.pdf
"Kava Dermopathy"
(http://www.ncbi.nlm.nih.gov/pubmed/8021378)
That being said, there was a pretty interesting suggestion made by Ruze that kava interferes with cholesterol metabolism which causes the skin changes which are similar to lipid-lowering drugs (referenced one in particular, triparanol).
This study, which studied the effect of triparanol on rat skin found results extremely similar to kava dermopathy.
http://www.jlr.org/content/4/2/160.full.pdf
"Kava Dermopathy"
(http://www.ncbi.nlm.nih.gov/pubmed/8021378)
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