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Any truth to this dated study?

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verticity

I'm interested in things
Don't know, it could be a rare adverse reaction, or it could be a case of correlation vs. causation, i.e., kava being blamed for something else that caused it. Or it could be somewhere in the middle, maybe kava exacerbated some existing condition the guy had. But when I read stuff like this:
One possible explanation for the rhabdomyolysis in this patient, Kamali said, was that the kava induced muscle weakness that led to over-exertion and stress as the bicyclist attempted to go about his normal routine. Alternatively, the kava might have caused direct muscle toxicity, or the kava might have contained a foreign impurity.
= three different highly speculative attempts to explain what happened, it leads me to believe they really have no effing idea what caused the guy's illness.
You can bet, though, that if the patient were a regular user of an approved pharmaceutical, say ibuprofen, to take a random example, it would not warrant a special case report about the demon NSAID.
 
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Rookietwoshoes

The creatine levels were through the roof though. It would be interesting to measure levels before and after ingestion.
 
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Rookietwoshoes

If kava is a diuretic then anyone with underlying kidney problems wouldn't benefit from drinking it. If it also increases creatine levels then it's a double whammy .I suppose this really emphasizes the fact that it's critical that one remain hydrated, particularly for those drinkers who may have undiagnosed kidney disease.

I see your point that they are pointing fingers at all herbal supplements. Unfortunately, all they have to go on is the patient's admission to ingesting twice the kava he was a customed to taking. Could there be a physiological impact to overdoing it?
 

sɥɐʞɐs

Avg. Dosage: 8 Tbsp. (58g)
Review Maestro
i speculate that kava might be harder on the kidneys than the liver. all kava.
 
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verticity

I'm interested in things
I agree the article does not prove causality, and does belong to the genre of sensationalist but insubstantial case reports about herbal remedies.

But, kava is a drug, as @Rookietwoshoes pointed out it's a diuretic among other things, which could have some effect on the kidneys. We simply don't have enough hard science on human subjects to make statements like that.

This calls for an army.. of human lab rats.

Edit: I should add, we actually do have evidence about the health effects of kava, but it is negative evidence, i.e. the absence of any epidemic of kava drinkers dropping dead from kidney failure in any significant numbers-- an experiment that has been ongoing for 3000 years.
 
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Rookietwoshoes

They could mention the actual dose, maybe his normal was 5mg from crappy kava tea bags and he had 10mg that day. Red meat can increase creatine levels; did he have a hamburger recently?

The article is titled "Medical Sleuthing Linked Muscle, Kidney Problems to Kava Tea", but in fact there is very little "sleuthing" and absolutely no "link". Utterly irresponsible journalism.
i don't think that a hamburger is going to raise creatine to those crazy levels.

It takes a lot of overexertion to induce rhab. All he did was ride a bike. Can kava cause that much muscle fatigue that moderate activity amounts to a lot ? That sounds like such a stretch. I remember a a few articles coming out about rhabdomyolisis after the crossfit gyms started sprouting up and people were ending up in the hospital as a result of overdoing it.
 
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Rookietwoshoes

@verticity - True. But maybe the American ideology of cumulative hyper dosing and overdoing it differs from that of the Islanders . I don't know. I guess the point is to 'stay hydrated '
 

kavadude

❦ॐ tanuki tamer
I've discussed this one before, but people have given themselves rhabdomyolysis through exercise alone. Google "crossfit rhabdo" for some fun afternoon reading. Adding a diuretic into the mix is inadvisable and I would not recommend kava before exercise, but I don't think there is enough here to implicate kava in any kind of way.
 

Prince Philip

Duke of Edinborogu
I think we've discussed the tea in the past. In additional to kava, it has carob, sarsaparilla, cinnamon, ginger, cardamom and stevia. That's assuming the brand is Yogi. If they're referring to what we squeeze as "tea," then they're using the term in a somewhat imprecise way considering kava teas exist.

I also don't think it's a quote-mine to say, "only one other case of myoglobinuria (muscle damage) has been reported. This is not to say it never happens, but we were fortunate to recognize it because it is so rare.”

All in all, I'd have to agree with @kavadude on this one - kava is used for post-exercise recovery, not pre-exercise whateverness.
 
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Rookietwoshoes

The point is education . The guy that riding the bike might not have known not to exercise after kava. Even Chris has admitted to going through several rounds of kidney stones as a result of drinking kava and not supplementing with additional water intake.
 

sumguy

Kava Enthusiast
So does the night before count as pre-exercise if I ride my bike to work the next morning?
 
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